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　　胃潰瘍指胃腸黏膜被胃消化液自身消化而造成的超過(guò)粘膜肌層的組織損傷，那么胃潰瘍?cè)趺粗委熥詈媚?今天小編為大家推薦治療女人胃潰瘍的方法。</p><h2> 　　治療女人胃潰瘍的方法</h2><p> 　　1、抑制胃酸分泌藥:目前臨床上主要有H2受體拮抗劑(H2-RA)及質(zhì)子泵抑制劑(PPI)。H2-RA可抑制基礎(chǔ)及刺激的胃酸分泌,常用的如西咪替丁、雷尼替丁、法莫替丁和尼扎替丁;PPI作用于壁細(xì)胞胃酸分泌終末步驟中的關(guān)鍵酶H+-K+ATP酶,使其不可逆失活,抑酸作用更強(qiáng)且作用持久。PPI促進(jìn)潰瘍愈合的速度較快、愈合率較高,適用于各種難治性潰瘍或NSAID潰瘍患者不能停用NSAID時(shí)的治療,還可與抗生素的協(xié)同作用可用于根除幽門(mén)螺桿菌治療,因此是胃潰瘍的首選用藥。常用的PPI有奧美拉唑、蘭索拉唑、雷貝拉唑、埃索美拉唑、艾普拉唑等。</p><p> 　　2、粘膜保護(hù)劑:目前已不屬于治療潰瘍的一線用藥,但與抑酸藥聯(lián)用后,其可提高潰瘍愈合質(zhì)量,減少潰瘍復(fù)發(fā),常見(jiàn)的如硫糖鋁、膠體鉍,枸櫞酸鉍鉀、米索前列醇等。</p><p> 　　3、胃腸動(dòng)力藥:主要用于出現(xiàn)惡心、嘔吐、腹脹等癥狀的患者以促進(jìn)胃腸排空,緩解癥狀。</p><p> 　　如前所述,幽門(mén)螺桿菌是胃潰瘍發(fā)生的重要原因之一,因此幽門(mén)螺桿菌陽(yáng)性的患者,應(yīng)予以根除幽門(mén)螺桿菌治療,其不僅可以促進(jìn)潰瘍愈合,還能預(yù)防潰瘍復(fù)發(fā),從而徹底治愈潰瘍。</p><p> 　　4、目前尚無(wú)單一藥物可有效根除幽門(mén)螺桿菌,因此必須聯(lián)合用藥。近年來(lái)國(guó)際上抗幽門(mén)螺桿菌相關(guān)指南及共識(shí),推薦的一線治療方案是以PPI為基礎(chǔ)加上兩種抗生素的三聯(lián)治療方案,療程7d~14d。臨床證實(shí)其具有療效高、耐受性和依從性好等優(yōu)點(diǎn)。具有殺滅幽門(mén)螺桿菌作用的抗生素有克拉霉素、阿莫西林、甲硝唑(或替硝唑)、四環(huán)素、呋喃唑酮、某些喹喏酮類(lèi)如左氧氟沙星等。PPI及膠體鉍體內(nèi)能抑制幽門(mén)螺桿菌,與上述抗生素有協(xié)同殺菌作用。潰瘍的治療療程一般為4-6周,部分需要維持8周,前2周一般為根除幽門(mén)螺旋桿菌的治療,隨后繼續(xù)予以抑制胃酸分泌及保護(hù)胃粘膜的藥物鞏固治療。由于治療周期相對(duì)較長(zhǎng),因此需要患者積極配合,堅(jiān)持服藥,只有這樣才能有效控制胃潰瘍的病情。</p><h2> 　　胃潰瘍的原因</h2><p> 　　胃腔內(nèi),胃酸和胃蛋白酶是胃液中重要的消化物質(zhì)。胃酸為強(qiáng)酸性物質(zhì),具有較強(qiáng)的侵蝕性;胃蛋白酶具有水解蛋白質(zhì)的作用,可破壞胃壁上的蛋白質(zhì),然而,在這些侵蝕因素的存在下,胃腸道仍能抵抗而維持黏膜的完整性及自身的功能,其主要是因?yàn)槲?、十二指腸黏膜還具有一系列防御和修復(fù)機(jī)制。我們將胃酸及胃蛋白酶的有害侵蝕性稱之為損傷機(jī)制,而將胃腸道自身具有的防御和修復(fù)機(jī)制稱之為保護(hù)機(jī)制。目前認(rèn)為,正常人的胃十二指腸黏膜的保護(hù)機(jī)制,足以抵抗胃酸及胃蛋白酶的侵蝕。但是,當(dāng)某些因素?fù)p害了保護(hù)機(jī)制中的某個(gè)環(huán)節(jié)就可能發(fā)生胃酸及蛋白酶侵蝕自身黏膜而導(dǎo)致潰瘍的形成。當(dāng)過(guò)度胃酸分泌遠(yuǎn)遠(yuǎn)超過(guò)黏膜的防御和修復(fù)作用也可能導(dǎo)致潰瘍發(fā)生。近年的研究已經(jīng)表明,幽門(mén)螺桿菌和非甾體抗炎藥是損害胃腸保護(hù)機(jī)制導(dǎo)致潰瘍發(fā)病的最常見(jiàn)病因,胃酸在潰瘍形成中起關(guān)鍵作用。此外,藥物,應(yīng)激,激素也可導(dǎo)致潰瘍的產(chǎn)生,各種心理因素及不良的飲食生活習(xí)慣可誘發(fā)潰瘍的出現(xiàn)。</p><h2> 　　胃潰瘍的特點(diǎn)</h2><p> 　　1、慢性過(guò)程:除少數(shù)較早就醫(yī)的患者外,多數(shù)患者病程已長(zhǎng)達(dá)幾年、十幾年或更長(zhǎng)時(shí)間。</p><p> 　　2、周期性:大多數(shù)患者病情反復(fù)發(fā)作,并且發(fā)作期與緩解期隨季節(jié)變換、精神緊張、情緒波動(dòng)、飲食不調(diào)或服用與發(fā)病有關(guān)的藥物等因素的變化互相交替出現(xiàn)。反映了潰瘍急性活動(dòng)期、逐漸愈合、形成瘢痕的潰瘍周期的反復(fù)過(guò)程。發(fā)作期可達(dá)數(shù)周甚至數(shù)月,緩解期可長(zhǎng)至數(shù)月或幾年。發(fā)作頻率及發(fā)作與緩解期維持時(shí)間,因患者的個(gè)體差異及潰瘍的發(fā)展情況和治療效果及鞏固療效的措施而異。</p><p> 　　3、節(jié)律性:潰瘍疼痛機(jī)制主要與過(guò)多的胃酸分泌刺激潰瘍面有關(guān),故不同部位的潰瘍病疼痛具有不同的規(guī)律性。胃潰瘍疼痛多在餐后半小時(shí)出現(xiàn),持續(xù)1～2小時(shí),逐漸消失,再次進(jìn)餐后疼痛重復(fù)出現(xiàn),如此反復(fù)循環(huán)。當(dāng)胃潰瘍位于幽門(mén)管處或者與十二指腸潰瘍同時(shí)并存時(shí),疼痛節(jié)律可與十二指腸潰瘍相同。但是,有些特殊類(lèi)型的潰瘍病的疼痛節(jié)律性不是很明顯,如老年人的潰瘍及十二指腸球后潰瘍等。值得注意的是當(dāng)疼痛的節(jié)律性突然發(fā)生變化時(shí),應(yīng)考慮病情有所發(fā)展,或可能出現(xiàn)其他的并發(fā)癥。</p><p> 　　4、疼痛的部位:胃潰瘍疼痛多位于劍突下(即通常所說(shuō)的心窩窩)正中或偏左,疼痛范圍一般較局限,局部有壓痛,但是疼痛的部位,并不一定就是潰瘍所在的部位。當(dāng)潰瘍深達(dá)漿膜層或?yàn)榇┩感詽儠r(shí),疼痛可擴(kuò)散至胸部、左上腹、右上腹或背部等身體其他部位。</p><p> 　　5、疼痛的性質(zhì)與程度:每個(gè)人對(duì)疼痛的耐受程度不一,故潰瘍病疼痛的程度沒(méi)有一個(gè)客觀的標(biāo)準(zhǔn),其性質(zhì)也視患者的感覺(jué)而定,通常被描述為饑餓樣不適感、鈍痛、噯氣、壓迫感、灼痛或劇痛和刺痛等。<br/> 猜您感興趣：</p><p 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